Amyotrophic lateral sclerosis (ALS) is a relatively rare neurological disorder. Its prevalence varies by region, and it's estimated to affect approximately two to four people per 100,000 in the general population. ALS is a global phenomenon, affecting individuals in various countries and regions around the world. The prevalence is relatively consistent in most countries, but it can vary to some extent.
There are some geographical variations in the prevalence of ALS. For example, countries in the western world, including the United States and Europe, tend to report higher prevalence rates. It's worth noting that these variations can be influenced by factors such as genetics, environmental factors, and diagnostic criteria.
ALS primarily affects adults, and the risk of developing the disease increases with age. It typically strikes individuals in mid-life, between the ages of 40 and 70. ALS is slightly more common in men than in women.
A small percentage of ALS cases, around 5-10%, are categorized as familial ALS (FALS), where the disease is inherited within families due to specific genetic mutations. The majority of ALS cases are considered sporadic, with no clear genetic link.
The incidence of ALS refers to the number of new cases diagnosed in a given population within a specified period. The incidence of ALS is estimated to be around 1-2 cases per 100,000 people per year.
People are diagnosed each year
Of cases have no genetic cause
Age range most people develop ALS